Biodistribution of 99mTc-Peptides 1 and 2 Radiolabeled Using EDDA as Coligand in CD1 Nude Mice Bearing AR42J Tumor Xenografts at 1 Hour After Injection
| Peptide | ||||
|---|---|---|---|---|
| Organ | 1 | 1 blocked | 2 | 2 blocked |
| Liver | 1.1 ± 0.3* | 0.5 ± 0.2 | 0.4 ± 0.1 | 0.3 ± 0.0 |
| Kidneys | 10.1 ± 0.7 | 11.6 ± 1.7 | 10.3 ± 0.5 | 12.0 ± 2.4 |
| Tumor | 1.5 ± 0.6* | 0.8 ± 0.1 | 2.6 ± 0.2* | 0.8 ± 0.2 |
| Blood | 0.5 ± 0.1 | 0.5 ± 0.2 | 0.4 ± 0.0 | 0.3 ± 0.0 |
| Stomach | 1.9 ± 0.1* | 0.4 ± 0.2 | 0.9 ± 0.5 | 0.4 ± 0.3 |
| Spleen | 0.5 ± 0.2* | 0.2 ± 0.1 | 0.2 ± 0.0 | 0.1 ± 0.1 |
| Intestine | 1.1 ± 0.1 | 0.8 ± 0.3 | 0.6 ± 0.3 | 0.4 ± 0.3 |
| Muscle | 0.1 ± 0.0 | 0.2 ± 0.1 | 0.1 ± 0.0 | 0.1 ± 0.0 |
| Pancreas | 0.3 ± 0.0 | 0.2 ± 0.1 | 0.3 ± 0.0* | 0.2 ± 0.0 |
↵* Significant, P = 0.05.
Values are expressed as %ID/g (mean ± SD, n = 3).