Biodistribution of 99mTc-Peptides 1 and 2 Radiolabeled Using Tricine as Coligand in CD1 Nude Mice Bearing AR42J Tumor Xenografts at 1 Hour After Injection
| Peptide | ||||
|---|---|---|---|---|
| Organ | 1 | 1 blocked | 2 | 2 blocked |
| Liver | 3.0 ± 0.7 | 7.6 ± 2.3 | 1.5 ± 1.3 | 2.2 ± 0.3 |
| Kidneys | 31.8 ± 5.1 | 35.9 ± 7.0 | 12.0 ± 1.6 | 19.1 ± 7.4 |
| Tumor | 0.8 ± 0.4 | 0.7 ± 0.20 | 1.7 ± 0.1* | 0.6 ± 0.2 |
| Blood | 0.9 ± 0.2 | 1.4 ± 0.6 | 0.4 ± 0.1 | 0.6 ± 0.1 |
| Stomach | 0.5 ± 0.6 | 0.9 ± 0.8 | 1.1 ± 0.3 | 0.6 ± 0.1 |
| Spleen | 0.6 ± 0.1 | 1.5 ± 0.1 | 0.5 ± 0.4 | 0.6 ± 0.1 |
| Intestine | 5.9 ± 0.4 | 10.5 ± 2.2 | 1.0 ± 0.1 | 2.8 ± 0.5 |
| Muscle | 0.2 ± 0.1 | 0.4 ± 0.1 | 0.1 ± 0.0 | 0.1 ± 0.1 |
| Pancreas | 0.4 ± 0.1 | 0.4 ± 0.3 | 0.2 ± 0.0 | 0.2 ± 0.1 |
↵* Significant, P = 0.05.
Values are expressed as %ID/g (mean ± SD, n = 3).