TABLE 1

Parameters Used in Decision Tree Modeling

Parameter	Baseline	Limits	Source
Prevalence of responders	0.49	0.44–0.55	Meta-analysis of studies 6–13
SPECT sensitivity	0.94	0.88–0.97	Meta-analysis of studies 6–13
SPECT specificity	0.90	0.83–0.94	Meta-analysis of studies 6–13
Cost of SPECT^*	265 (∼379)		NICE guidelines (22)
Cost of chemotherapy^*	6,283 (∼8,985)		HTA report (23)
Cost of basic supportive care^*	3,210 (∼4,590)		HTA report (23)
Life expectancy of basic supportive care	0.433 y		HTA report (23)
Life expectancy with treatment success adjusted for prevalence of responders	1.13 y		HTA report (23)