TABLE 2

Individual Parameter Estimates Derived from Reduced Compartmental Model

Patient no.	Lesion	K1 (mL/g/min)	k2 (min⁻¹)	k3 (min⁻¹)	K (mL/g/min)	Patlak slope
1	Thymic cyst	0.012	0.092	0.019	0.0021	0.0017
2	Hamartoma	0.098	0.292	0.006	0.0019	0.0016
3	Metastasis	0.098	0.279	0.006	0.0020	0.0007
4	NSCLC^*	0.170	0.179	0.008	0.0070	0.0051
5	1-NSCLC	0.287	0.195	0.017	0.0236	0.0108
	2-NSCLC	0.187	0.170	0.022	0.0213	0.0074
6	1-NSCLC	0.073	0.067	0.01	0.0096	0.0088
	2-NSCLC	0.128	0.131	0.015	0.0129	0.0107
	3-NSCLC	0.104	0.105	0.014	0.0125	0.0095
	4-NSCLC	0.064	0.117	0.017	0.0082	0.0043
	5-NSCLC	0.063	0.036	0.006	0.0092	0.0035
7	NSCLC^†	0.082	0.210	0.008	0.0031	0.0030
8	1-NSCLC	0.176	0.131	0.011	0.0134	0.0074
	2-NSCLC^*	0.275	0.211	0.004	0.0053	0.0058
9	1-NSCLC	0.242	0.213	0.037	0.0359	0.0180
	2-NSCLC	0.184	0.151	0.026	0.0266	0.0152
10	1-NSCLC	0.114	0.070	0.011	0.0145	0.0078
	2-NSCLC^*	0.151	0.201	0.01	0.0075	0.0034
Total Mean	NSCLC	0.153	0.146	0.014	0.0140	0.0081
Total SD		0.073	0.058	0.008	0.0091	0.0043
Mean for unaffected lungs		0.036	0.208	—	—	—
SD for unaffected lungs		0.014	0.047	—	—	—

↵* High initial uptake, subsequent tracer washout.
↵† Small tumor size (volume, ∼0.8 cm³), possible image distortions because of partial-volume effect.