Radiochemical Purity of 111In-Radiolabeled Antibodies Determined by Thin-Layer Chromatography
| Antibody format | 111In-Antibody | 111In-CHX-A″-DTPA | Free 111In |
|---|---|---|---|
| scFv 19G9 | 98.20% | 0.49% | 1.31% |
| Diabody 19G9 | 99.72% | 0.12% | 0.16% |
| Miniantibody 19G9 | 99.10% | 0.70% | 0.29% |
| IgG 19G9 | 99.79% | 0.08% | 0.13% |
Values are based on percentage of total counts in 1-μL sample as free 111In, free radiolabeled DTPA, and radiolabled antibody.