Univariate and Multivariate Cox Proportional Hazard Regression Analysis of Cardiac Death According to MPR
| Univariate analysis | Age- and sex-adjusted analysis | |||
|---|---|---|---|---|
| Variable | Hazard ratio | P | Hazard ratio | P |
| MPR (per SD) | 4.18 (3.05–5.74) | <0.001 | 4.11 (2.98–5.67) | <0.001 |
| Family history (yes) | 0.56 (0.32–0.98) | 0.043 | 0.68 (0.38−1.21) | 0.191 |
| Previous myocardial infarction (yes) | 6.06 (2.20–16.71) | 0.001 | 5.21 (1.87–14.54) | 0.002 |
| LVEF (per SD) | 2.79 (2.02–3.85) | <0.001 | 2.76 (2.00–3.82) | <0.001 |
| LVEDV (per 10 mL) | 1.05 (1.03–1.08) | <0.001 | 1.06 (1.04–1.08) | <0.001 |
| Aspirin (yes) | 0.41 (0.24–0.67) | 0.001 | 0.40 (0.24–0.68) | <0.001 |
| Diuretics (yes) | 5.58 (3.17–9.81) | <0.001 | 5.58 (3.15–9.91) | <0.001 |
| Digoxin (yes) | 4.97 (2.94–8.39) | <0.001 | 4.94 (2.90–8.40) | <0.001 |
| Matching (per 10%) | 1.40 (1.20–1.64) | <0.001 | 1.41 (1.20–1.66) | <0.001 |
| Mismatching (per 10%) | 1.20 (0.95–1.51) | 0.134 | 1.16 (0.91–1.50) | 0.226 |
CI = confidence interval; LVEDV = left ventricular end-diastolic volume.
Data in parentheses are 95% confidence intervals.