Patient Characteristics for Each Tertile of MPR
Characteristic | MPR, first tertile (<1.49) (n = 114) | MPR, second tertile (1.49–1.84) (n = 116) | MPR, third tertile (>1.84) (n = 114) | Total (n = 344) | P |
---|---|---|---|---|---|
Age (y) | 69 ± 11 | 68 ± 10 | 62 ± 11 | 66 ± 11 | <0.001 |
Sex (F/M) (n) | 22/92 | 26/90 | 25/89 | 73/271 | 0.628 |
Hypercholesterolemia (%) | 54 | 53 | 64 | 57 | 0.141 |
Smoking (%) | 31 | 28 | 38 | 33 | 0.323 |
Diabetes mellitus (%) | 12 | 17 | 10 | 13 | 0.539 |
Hypertension (%) | 28 | 29 | 29 | 29 | 0.884 |
Family history (%) | 32 | 40 | 54 | 42 | 0.001 |
Previous myocardial infarction (%) | 82 | 71 | 61 | 71 | <0.001 |
Previous CABG (%) | 29 | 31 | 26 | 29 | 0.661 |
Previous PCI (n) | 44 | 42 | 48 | 45 | 0.506 |
LVEF (%) | 30 ± 14 | 37 ± 13 | 41 ± 17 | 36 ± 15 | <0.001 |
Typical anginal complaints (%) | 77 | 85 | 81 | 81 | 0.747 |
Left ventricular end-diastolic volume (mL) | 172 ± 91 | 124 ± 62 | 124 ± 81 | 140 ± 82 | <0.001 |
Aspirin (%) | 54 | 68 | 68 | 63 | 0.040 |
Coumarin (%) | 44 | 29 | 25 | 33 | 0.003 |
Statin (%) | 52 | 48 | 61 | 54 | 0.185 |
Diuretic (%) | 47 | 31 | 24 | 34 | <0.001 |
Digoxin (%) | 22 | 11 | 8 | 14 | 0.002 |
β-blocker (%) | 64 | 70 | 60 | 65 | 0.489 |
Angiotensin-converting enzyme-inhibitor/ARB (%) | 58 | 40 | 42 | 47 | 0.017 |
Matching defect (% left ventricle) | 30 ± 15 | 27 ± 15 | 25 ± 17 | 27 ± 16 | 0.012 |
Location of matching defects: LAD/LCX/RCA area (%) | 29/33/44 | 34/30/55 | 32/18/51 | 31/27/50 | 0.669/0.007/0.290 |
Mismatching defect (% left ventricle) | 11 ± 10 | 8 ± 10 | 7 ± 9 | 9 ± 10 | 0.011 |
Location of mismatching defects: LAD/LCX/RCA area (%) | 27/37/33 | 26/24/28 | 14/33/22 | 22/31/28 | 0.017/0.393/0.055 |
Normal area of left ventricle (%) | 59 ± 19 | 65 ± 19 | 68 ± 21 | 64 ± 20 | 0.001 |
Myocardial perfusion at rest (mL/min/100 g) | 96 ± 23 | 85 ± 22 | 80 ± 21 | 87 ± 23 | <0.001 |
Myocardial perfusion during stress (mL/min/100 g) | 117 ± 34 | 139 ± 36 | 177 ± 45 | 145 ± 46 | <0.001 |
ARB = angiotensin type I receptor blocker; LAD = left anterior descending coronary artery; LCX = circumflex coronary artery; RCA = right coronary artery.
Categoric variables are show as percentage or as number; continuous variables as mean ± SD.