Prediction of Long-Term Prognosis According to Univariate Analysis
Sudden death or ventricular arrhythmic events over 11 y of follow-up | Hazard ratio, with 95% CI | ||||
---|---|---|---|---|---|
Variable | Present | Absent | χ2 | P | |
H/M ratio < 2.8 | 18/40 (45%) | 6/46 (13%) | 4 (1.6–10) | 8.5 | 0.004 |
LVEF < 50% | 9/15 (60%) | 15/71 (21.1%) | 1.6 (1.3–7) | 6.9 | 0.008 |
H/M ratio < 2.8 and LVEF < 50% | 9/12 (75%) | 15/74 (20.3%) | 4.4 (1.9–9.9) | 12.1 | <0.0001 |
History of dilated cardiomyopathy | 7/11 (63.6%) | 17/75 (22.7%) | 2.8 (1.2–6.8) | 5.3 | 0.021 |
History of structural heart disease | 11/23 (47.8%) | 13/63 (20.6%) | 2.3 (1–5.2) | 4.3 | 0.038 |
Older age (≥65 y) | 5/18 (27.8%) | 19/68 (27.9%) | 1.0 (0.4–2.6) | 0.09 | NS |
Male | 17/56 (30.4%) | 7/30 (23.3%) | 1.3 (0.6–3.3) | 0.44 | NS |
History of ischemic heart disease | 1/7 (14.3%) | 23/79 (29.1%) | 2.2 (0.3–16.4) | 0.6 | NS |
History of hypertrophic cardiomyopathy | 2/4 (50%) | 22/82 (26.8%) | 2.3 (0.5–9.7) | 1.2 | NS |
History of genetic arrhythmogenic disorder | 4/9 (44.4%) | 20/77 (25.9%) | 2.2 (0.7–6.4) | 2 | NS |
History of congenital heart disease | 4/7 (57.1%) | 20/79 (42.9%) | 2 (0.7–6) | 1.7 | NS |
Use of β-blocker | 10/24 (41.7%) | 14/62 (22.6%) | 1.7 (0.8–3.9) | 1.7 | NS |
CI = confidential interval; NS = not significant.