Performance of 18F-FDG PET Scans 3, 6, 9, and 12 Months After Curative Treatment
| Index | PET 1 (n = 48) | PET 2 (n = 40) | PET 3 (n = 35) | PET 4 (n = 33) |
|---|---|---|---|---|
| True-positives | 14 | 8 | 4 | 4 |
| False-positives | 9 [4]* | 9 [6]* | 10 [7]* | 7 [3]* |
| False-negatives | 1 | — | — | — |
| True-negatives | 24 | 23 | 21 | 22 |
| Sensitivity | 93% | 100% | 100% | 100% |
| Specificity | 73% | 72% | 68% | 76% |
| PPV | 61% | 47% | 29% | 36% |
| NPV | 96% | 100% | 100% | 100% |
| Accuracy | 79% | 78% | 71% | 79% |
| Change in diagnostic strategy | 20/48 (42%) | 13/40 (33%) | 9/35 (26%) | 8/33 (24%) |
| Superfluous change | 7/20 (35%) | 6/13 (46%) | 7/9 (78%) | 4/8 (50%) |
| Newly detected malignancy | 14 | 2 | 1 | 1 |
| Confirmation at time of PET | 8 | 4 | 2 | 3 |
| Curative treatment | 2 | 2 | 2 | 1 |
| Alive without malignancy | 2 | 0 | 1 | 1 |
↵* Numbers in brackets are false-positives with known anatomic substrate, nonmalignant.