TABLE 3

Literature Review of Publications on Population-Based APTACs and IDIFs

ReferencenMethodCalibrationAUCMRglc
Takikawa et al. (13)10/24Arithmetic mean2 arterial0.9980.992
1 AVS0.9980.989
Tsuchida et al. (14)44/10Arithmetic mean+3.5% ± 2.2%+2.9% ± 1.9%
Shiozaki et al. (15)101/192Arithmetic meanAA/iDV+7.2% ± 5.7%+8.9% ± 7.3%
Bentourkia et al. (29)20/same 20Fit to equation0.998
Eberl et al. (17)26/26Fit to equation2 AVS0.995
de Geus-Oei et al. (9)136IDIF0.98
This study80/40Fit to equationAA/iDV0.8800.963
1 arterial0.9940.994
IDIF0.8560.966
  • n = no. of patients (to derive curve/to validate curve); AUC = correlation or mean % difference between AUC of population-based curve and serial arterial sampling; MRglc = correlation or mean % difference between glucose metabolic rate of population-based curve and serial arterial sampling; AVS = arterialized venous samples; AA/iDV = administered activity/initial distribution volume of 18F-FDG.