TABLE 2

Biodistribution of ¹⁷⁷Lu-AMBA (0.185 MBq) in LNCaP, DU145, and PC-3 Tumor–Bearing Mice

	1 h after dose			24 h after dose
Organ	LNCaP (n = 6)	DU145 (n = 8)	PC-3^* (n = 9)	LNCaP (n = 6)	DU145 n = 8)	PC-3^* (n = 9)
Tumor (%ID/g)	1.52 ± 0.94	0.95 ± 0.23	6.35 ± 2.23	0.83 ± 0.18	0.52 ± 0.22	3.39 ± 0.85
Blood (%ID/g)	0.16 ± 0.08	0.20 ± 0.06	0.46 ± 0.20	0.01 ± 0.01	0.01 ± 0.01	0.03 ± 0.02
Liver (%ID/organ)	0.21 ± 0.09	0.24 ± 0.10	0.25 ± 0.08	0.07 ± 0.03	0.08 ± 0.03	0.21 ± 0.36
Kidneys (%ID/organ)	2.84 ± 0.07	4.21 ± 1.80	2.95 ± 0.79	1.09 ± 0.14	0.92 ± 0.17	0.91 ± 0.25
Pancreas (%ID/organ)	14.65 ± 3.07	17.14 ± 2.54	17.78 ± 4.07	11.86 ± 2.83	12.41 ± 2.05	12.28 ± 3.50
Gastrointestinal (%ID/organ)	15.19 ± 2.62	10.91 ± 1.45	11.22 ± 3.29	7.21 ± 0.48	5.17 ± 0.86	5.77 ± 1.79
Skin (%ID/g)	0.30 ± 0.12	0.46 ± 0.27	0.33 ± 0.13	0.08 ± 0.02	0.07 ± 0.02	0.10 ± 0.02
Muscle (%ID/g)	0.08 ± 0.04	0.10 ± 0.03	0.09 ± 0.02	0.02 ± 0	0.01 ± 0.01	0.03 ± 0.02
Bladder/urine (%ID/organ)	62.00 ± 2.00	44.3 ± 10.38	55.66 ± 7.28	NA	NA	NA

↵* Data presented are from Lantry et al. (11).
NA = not applicable.