TABLE 4

Comparison of 4FMFES Radiation Dosimetry Estimates Between Subjects with Intact Gallbladder, Using Various Gallbladder Models, and Subjects with Prior Cholecystectomy

	Subjects with intact gallbladder (n = 8)
Organ	No gallbladder model	Gallbladder-voiding model^*	Simulated cholecystectomy^†	Subjects with prior cholecystectomy (n = 2)
Absorbed dose (mGy/MBq ± SD)^‡
Adrenals	0.020 ± 0.002	0.019 ± 0.001	0.016 ± 0.001	0.016 ± 0.001
Gallbladder wall	0.988 ± 0.348	0.709 ± 0.247	—	—
Lower large intestine	0.038 ± 0.010	0.046 ± 0.007	0.066 ± 0.004	0.063 ± 0.009
Small intestine	0.104 ± 0.027	0.127 ± 0.020	0.184 ± 0.014	0.173 ± 0.028
Upper large intestine	0.117 ± 0.028	0.141 ± 0.020	0.200 ± 0.015	0.187 ± 0.031
Ovaries	0.025 ± 0.004	0.029 ± 0.003	0.038 ± 0.002	0.037 ± 0.004
Pancreas	0.026 ± 0.003	0.024 ± 0.002	0.018 ± 0.000	0.017 ± 0.001
Uterus	0.024 ± 0.004	0.027 ± 0.003	0.033 ± 0.004	0.034 ± 0.006
Effective dose (mSv/MBq ± SD)	0.025 ± 0.003	0.027 ± 0.002	0.033 ± 0.001	0.031 ± 0.002

↵* Gallbladder-voiding model: 50% of gallbladder activity was transferred to intestines every 3 h.
↵† Simulated cholecystectomy: total gallbladder activity was transferred to intestines.
↵‡ For all other organs, absorbed dose varied by less than 12% when either gallbladder model was applied.