TABLE 1

Group Differences Detected with BPF-WM and BPF

BPF-WM (mL/mL)BPF (mL/mL)*
RegionControlsPatientsPEffect sizePEffect size
I. sup. temporal90 ± 2677 ± 320.214−0.530.280−0.50
C. sup. temporal86 ± 2474 ± 270.199−0.520.264−0.49
I. mid. temporal97 ± 2880 ± 290.113−0.600.154−0.57
C. mid. temporal93 ± 2478 ± 250.096−0.650.135−0.63
I. inf. temporal103 ± 2980 ± 280.034−0.780.052−0.76
C. inf. temporal100 ± 2691 ± 320.423−0.320.528−0.29
I. fusiform128 ± 3582 ± 24<0.001−1.35<0.001−1.34
C. fusiform122 ± 3297 ± 320.041−0.780.058−0.76
I. parahippocampus146 ± 3884 ± 26<0.001−1.62<0.001−1.62
C. parahippocampus146 ± 42103 ± 290.002−1.020.003−1.02
I. hippocampus129 ± 2966 ± 31<0.001−2.20<0.001−2.22
C. hippocampus126 ± 3499 ± 300.025−0.790.035−0.78
I. amygdala75 ± 1751 ± 200.002−1.390.005−1.37
C. amygdala77 ± 1662 ± 220.045−0.940.078−0.89
I. insula97 ± 2864 ± 210.001−1.180.001−1.17
C. insula97 ± 2767 ± 200.001−1.110.002−1.10
I. frontal70 ± 1868 ± 230.643−0.160.820−0.11
C. frontal67 ± 1764 ± 230.648−0.160.828−0.11
I. parietal65 ± 1865 ± 220.9140.010.8900.06
C. parietal64 ± 1868 ± 240.7610.200.5930.26
I. occipital41 ± 1145 ± 130.5240.390.2980.51
R. occipital39 ± 847 ± 160.2351.020.1301.10
  • * Values obtained using VND as estimate of nondisplaceable binding (10).

  • I. = ipsilateral to focus; sup. = superior; C. = contralateral to focus; mid. = middle; inf. = inferior.