TABLE 3

Radiochemical Yields of 18F-12 and By-Product A with Variations in Temperature

Mean ± SD (%)
Temperature (°C)18F-12By-product A
10043.5 ± 2.33.6 ± 0.7
11059.5 ± 2.111.5 ± 1
12050.0 ± 2.79.3 ± 2.8
13047.6 ± 10.312.6 ± 5.6
14039.4 ± 16.439.3 ± 19.1
  • [12] = 14.25 mmol/L, [TBAHCO3] = 25 mmol/L, DMF, 10 min (n = 3), analysis by TLC.