Radiochemical Yields of 18F-12 and By-Products in Different Solvents
| Mean ± SD (%) | |||
|---|---|---|---|
| Solvent | 18F-12 | By-product A | By-product B |
| Acetonitrile* | 0.8 ± 0.2 | ||
| DMAA | 26.6 ± 3.5 | 2.7 ± 0.7 | 13.4 ± 2.0 |
| DMSO | 25.4 ± 7.1 | 6.4 ± 2.9 | 14.9 ± 4.9 |
| DMF | 50.0 ± 2.7 | 9.3 ± 2.8 | |
↵* 82°C.
[12] = 14.25 mmol/L, [TBAHCO3] = 25 mmol/L, 120°C, 10 min (n = 3), analysis by TLC.