Neuropathologic and Imaging Findings of Subjects with Autopsy
| Subject | |||||
|---|---|---|---|---|---|
| Finding | 1 | 2 | 3 | 4 | 5 |
| Clinical diagnosis | DLB | DLB | DLB | AD | DLB |
| Amyloid-β plaques | + | — | ++ | + | ++ |
| Tau protein | — | — | + | + | — |
| Nigral neuronal loss | ++ | +++ | ++ | — | +++ |
| Cortical Lewy bodies | ++ | ++ | +++ | — | +++ |
| β-CIT V3″ | 2.7 | 2.14 | 2.09 | 6.72 | 3.67 |
| 18F-FDG PET | |||||
| Lateral occipital cortex | 0.74 | 0.68 | 0.80 | 0.85 | 0.81 |
| Ratio of posterior cingulate/precuneus + cuneus | 0.69 | 1.02 | 1.07 | 0.51 | 1.00 |
| Visual 18F-FDG PET | |||||
| Diagnosis | DLB | DLB | DLB | AD | DLB |
| Cingulate island sign | Y | Y | Y | N | Y |
| Final clinicopathologic diagnosis | DLB | DLB | DLB | AD | DLB |
+ = mild; — = absent; ++ = moderate; +++ = severe; Y = yes; N = no.