TABLE 3

Diagnostic Accuracy in Differentiating High- and Low-Risk Carcinoma

	Sensitivity		Specificity		PPV		NPV		Accuracy
Parameter	n	95% CI (%)	n	95% CI (%)	n	95% CI (%)	n	95% CI (%)	n	95% CI (%)
¹⁸F-FDG–to–¹⁸F-FES ratio (2.0)^*	8/11 (73%)	39–94	11/11 (100%)	76–100	8/8 (100%)	69–100	11/14 (79%)	49–95	19/22 (86%^‡)	65–97
¹⁸F-FES SUV (4.4)^*	9/11 (82%)	48–97	8/11 (73%)	39–94	9/12 (75%)	43–95	8/10 (80%)	44–97	17/22 (77%)	55–92
¹⁸F-FDG SUV (4.0)^*	11/11 (100%)	76–100	4/11 (36%)	11–69	11/18 (61%)	36–83	4/4 (100%)	47–100	15/22 (68%^‡)	45–86
MRI^†	4/8 (50%)	16–84	13/14 (93%)	66–100	4/5 (80%)	28–99	13/17 (76%)	50–93	17/22 (77%)	55–92

↵* Optimal cutoff value.
↵† Discrimination of stage ≥ Ic from ≤ Ib irrespective of histologic grade.
↵‡ P < 0.005 in comparison between ¹⁸F-FDG–to–¹⁸F-FES ratio and ¹⁸F-FDG SUV using McNemar test.
PPV = positive predictive value; NPV = negative predictive value.