Genes That Are Transcriptionally Activated by HIF-1
| Category | Gene(s) |
|---|---|
| Glucose metabolism | GLUT1, GLUT3 |
| HK1, HK2 | |
| GPI | |
| PFK1, PFK2 | |
| Aldose-A | |
| TPI | |
| GAPDH | |
| PGK1 | |
| PGM | |
| Enolase-1 | |
| PK-M | |
| LDHA | |
| CA9 | |
| Metastasis | CATHD |
| Collagen V | |
| MMP2 | |
| UPAR | |
| PAI1 | |
| LRP1 | |
| AMF/GPI | |
| MIC2 | |
| Cell proliferation | Cyclin G2 |
| IGF2 | |
| IGF-BP | |
| TGF-α | |
| TGF-β | |
| Cell survival/angiogenesis | ADM |
| EPO | |
| NOS2 | |
| VEGF | |
| LEP | |
| LRP1 | |
| Iron metabolism | Transferrin |
| Tf receptor | |
| Ceruloplasmin | |
| Drug resistance | MDR1 |