Biodistribution of 18F-ML-10 in Healthy Rats
| Mean ± SD %ID/g of tissue (n = 5) at: | ||||||
|---|---|---|---|---|---|---|
| Organ | 5 min | 15 min | 30 min | 60 min | 120 min | 240 min |
| Blood | 1.70 ± 0.35 | 0.92 ± 0.13 | 0.82 ± 0.08 | 0.36 ± 0.09 | 0.36 ± 0.09 | 0.36 ± 0.09 |
| Heart | 0.52 ± 0.14 | 0.30 ± 0.05 | 0.24 ± 0.40 | 0.11 ± 0.02 | 0.03 ± 0.00 | 0.02 ± 0.00 |
| Bone | 0.17 ± 0.05 | 0.18 ± 0.07 | 0.11 ± 0.01 | 0.08 ± 0.02 | 0.03 ± 0.00 | 0.05 ± 0.02 |
| Brain | 0.05 ± 0.01 | 0.03 ± 0.01 | 0.02 ± 0.10 | 0.02 ± 0.01 | 0.01 ± 0.00 | 0.01 ± 0.00 |
| Muscle | 0.23 ± 0.07 | 0.13 ± 0.03 | 0.10 ± 0.02 | 0.07 ± 0.02 | 0.02 ± 0.00 | 0.03 ± 0.01 |
| Spleen | 0.27 ± 0.09 | 0.16 ± 0.02 | 0.12 ± 0.10 | 0.07 ± 0.02 | 0.02 ± 0.00 | 0.02 ± 0.01 |
| Lung | 0.99 ± 0.43 | 0.55 ± 0.13 | 0.40 ± 0.07 | 0.25 ± 0.06 | 0.06 ± 0.01 | 0.06 ± 0.01 |
| Liver | 0.42 ± 0.10 | 0.28 ± 0.06 | 0.22 ± 0.05 | 0.09 ± 0.02 | 0.03 ± 0.00 | 0.02 ± 0.00 |
| Intestine | 0.29 ± 0.07 | 0.17 ± 0.03 | 0.19 ± 0.07 | 0.17 ± 0.11 | 0.08 ± 0.06 | 0.04 ± 0.01 |
| Kidney | 2.71 ± 0.88 | 2.33 ± 1.47 | 1.00 ± 0.09 | 0.55 ± 0.14 | 0.12 ± 0.00 | 0.05 ± 0.01 |