3H-ML-10 Uptake in Jurkat Cells in Response to Induction and Inhibition of Apoptosis vs. Induction of Necrosis
| Experiment and cells | Mean ± SD % uptake/108 cells | Treatment | Inhibition |
|---|---|---|---|
| Induction of apoptosis | |||
| Control | 0.206 ± 0.010 | ||
| Treated | 1.873 ± 0.066* | Anti-Fas antibody (CD95) | |
| Inhibition of apoptosis | |||
| Control | 0.275 ± 0.002 | Z-VAD-FMK | |
| Treated | 0.250 ± 0.012 | Anti-Fas antibody (CD95) | Z-VAD-FMK |
| Induction of necrosis | |||
| Control | 0.246 ± 0.019 | ||
| Treated | 0.141 ± 0.070 | Freeze–thaw |
↵* P < 0.001 compared with control group.