TABLE 4

Summary of Absorbed Dose Estimates (mGy/MBq) to Whole Body, Red Marrow, and Liver for ¹¹¹In-huJ591 and ⁹⁰Y-huJ591

		Administered antibody mass
Site	Isotope	10 mg	25 mg	50 mg	100 mg
Whole body^*	¹¹¹In	0.111 (±0.003)	0.119 (±0.003)	0.125 (±0.002)	0.123 (±0.006)
	⁹⁰Y	0.50 (±0.01)	0.55 (±0.01)	0.58 (±0.01)	0.57 (±0.03)
Red marrow^*	¹¹¹In	0.111 (±0.004)	0.132 (±0.005)	0.146 (±0.004)	0.147 (±0.008)
	⁹⁰Y	0.55 (±0.03)	0.73 (±0.04)	0.86 (±0.04)	0.90 (±0.06)
Liver^†	^†¹¹¹In	0.75 (±0.03)	0.56 (±0.03)	0.48 (±0.04)	0.37 (±0.04)
	^†⁹⁰Y	5.7 (±0.3)	4.1 (±0.3)	3.4 (±0.4)	2.5 (±0.3)
Lesion	⁹⁰Y	58 (±32)	78 (±45)	97 (±53)	95 (±53)

↵* All intergroup differences were statistically significant (P < 0.05) by paired t test except for 25 vs. 100 mg and 50 vs. 100 mg.
↵† All intergroup differences were statistically significant (P < 0.05) by paired t test except for 25 vs. 50 mg. Values quoted are mean (± SEM).