TABLE 2

Biodistribution of 7α-¹⁸F-FM-norT (¹⁸F-6)

	%ID/g^*
Tissue	1 h	1-h block^†	2 h	2-h block^†
Blood	0.11 ± 0.029	0.080 ± 0.020	0.057 ± 0.0086	0.055 ± 0.017
Liver	0.71 ± 0.13	0.49 ± 0.093	0.37 ± 0.076	0.39 ± 0.10
Kidney	0.58 ± 0.11	0.38 ± 0.069	0.34 ± 0.072	0.29 ± 0.13
Muscle	0.10 ± 0.020	0.069 ± 0.013	0.052 ± 0.0073	0.048 ± 0.021
Bone	0.55 ± 0.36	0.50 ± 0.17	0.65 ± 0.29	0.62 ± 0.19
Prostate	0.53 ± 0.17	0.19 ± 0.060	0.36 ± 0.12	0.065 ± 0.020
Prostate-to-blood	4.8 ± 2.0	2.4 ± 0.99	6.3 ± 2.2	1.2 ± 0.53
Prostate-to-muscle	5.3 ± 2.0	2.8 ± 1.0	6.9 ± 2.5	1.4 ± 0.76

↵* n = 5. All rats were treated with diethylstilbestrol 24 and 3 h before injection with ¹⁸F-labeled androgen.
↵† To block receptor-mediated uptake, 36 μg of dihydrotestosterone were added to each injected dose.