TABLE 1

Biodistribution of 7α-¹⁸F-FM-DHT (¹⁸F-5)

	%ID/g ± SEM^*
Tissue	1 h	1-h block^†	2 h	2-h block^†
Blood	0.056 ± 0.019	0.056 ± 0.036	0.027 ± 0.0070	0.028 ± 0.015
Liver	0.54 ± 0.16	0.68 ± 0.44	0.40 ± 0.16	0.33 ± 0.93
Kidney	0.27 ± 0.074	0.34 ± 0.21	0.17 ± 0.042	0.15 ± 0.095
Muscle	0.036 ± 0.012	0.045 ± 0.020	0.024 ± 0.012	0.018 ± 0.010
Bone	0.30 ± 0.057	0.34 ± 0.15	0.37 ± 0.050	0.35 ± 0.037
Prostate	0.29 ± 0.21	0.19 ± 0.072	0.22 ± 0.059	0.12 ± 0.051
Prostate-to-blood	5.2 ± 4.2	3.4 ± 2.5	8.1 ± 3.0	4.3 ± 3.0
Prostate-to-muscle	5.8 ± 4.6	4.2 ± 2.4	9.2 ± 5.2	6.7 ± 4.8

↵* n = 5. All rats were treated with diethylstilbestrol 24 and 3 h before injection with ¹⁸F-labeled androgen.
↵† To block receptor-mediated uptake, 36 μg of dihydrotestosterone were added to each injected dose.