%ID/g | ||||
---|---|---|---|---|
Tissue | 10 min | 30 min | 1 h | 2 h |
Blood | 0.15 ± 0.04 | 0.08 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.01 |
(+lisinopril) | 0.14 ± 0.04 | 0.02 ± 0.01 | 0.01 ± 0.01 | 0.02 ± 0.01 |
Heart | 0.39 ± 0.06 | 0.21 ± 0.04 | 0.15 ± 0.03 | 0.09 ± 0.02 |
(+lisinopril) | 0.07 ± 0.03 | 0.03 ± 0.03 | 0.00 ± 0.01 | 0.03 ± 0.01 |
Lungs | 15.20 ± 7.36 | 7.05 ± 1.97 | 5.91 ± 1.55 | 3.93 ± 1.17 |
(+lisinopril) | 0.17 ± 0.06 | 0.03 ± 0.01 | 0.04 ± 0.06 | 0.02 ± 0.01 |
Liver | 0.82 ± 0.13 | 0.59 ± 0.18 | 0.34 ± 0.06 | 0.17 ± 0.03 |
(+lisinopril) | 2.46 ± 1.15 | 0.29 ± 0.07 | 0.15 ± 0.14 | 0.08 ± 0.01 |
Spleen | 0.89 ± 0.12 | 0.65 ± 0.18 | 0.01 ± 0.06 | 0.19 ± 0.03 |
(+lisinopril) | 0.06 ± 0.01 | 0.01 ± 0.01 | 0.00 ± 0.01 | 0.03 ± 0.01 |
Kidneys | 1.21 ± 0.27 | 1.33 ± 0.46 | 1.30 ± 0.38 | 0.46 ± 0.14 |
(+lisinopril) | 0.54 ± 0.08 | 0.16 ± 0.02 | 0.13 ± 0.02 | 0.08 ± 0.02 |
Large intestine | 0.18 ± 0.05 | 0.17 ± 0.16 | 0.08 ± 0.02 | 0.10 ± 0.13 |
(+lisinopril) | 0.04 ± 0.02 | 0.02 ± 0.00 | 0.03 ± 0.03 | 0.17 ± 0.32 |
Small intestine | 1.86 ± 0.77 | 3.41 ± 1.18 | 6.02 ± 0.55 | 6.13 ± 1.36 |
(+lisinopril) | 5.19 ± 2.16 | 6.99 ± 2.39 | 6.67 ± 1.94 | 11.36 ± 1.51 |
Skeletal muscle | 0.41 ± 0.07 | 0.44 ± 0.16 | 0.36 ± 0.04 | 0.28 ± 0.02 |
(+lisinopril) | 0.08 ± 0.05 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.04 ± 0.01 |
Adipose | 0.24 ± 0.09 | 0.29 ± 0.09 | 0.29 ± 0.14 | 0.32 ± 0.06 |
(+lisinopril) | 0.07 ± 0.02 | 0.01 ± 0.01 | 0.01 ± 0.02 | 0.06 ± 0.03 |
Data are mean ± SD.