Outcomes of 2,009 Live Births as Function of Radioiodine Exposure
Radiation dose, in mGy, to ovaries (range) | % (no.) with: | ||||||||
---|---|---|---|---|---|---|---|---|---|
Factor (overall population) | No. of live births | % of girls | Term of <37 wk | Low birth weight | Death at <1 y | Malformation | Thyroid disease | Cancer | |
Before any treatment | 1,633 | 49.3 | 7.0 (114) | 10.3 (168) | 1.4 (22) | 4.2 (68) | 2.1 (34) | 0.4 (6) | |
After surgery for thyroid cancer | 376 | 45.3 | 12.8 (44) | 8.6 (33) | 0.8 (3) | 2.9 (11) | 2.1 (8) | 0.5 (2) | |
Cumulative radioiodine activity before conception (MBq) | |||||||||
0 | 0 | 67 | 40.6 | 6.0 | 7.5 | 0.0 | 3.0 | 0.0 | 0.0 |
<370 | 7 (0–13) | 121 | 50 | 11.6 | 13.2 | 1.6 | 1.7 | 4.0 | 2.4 |
370–3,700 | 85 (14–140) | 49 | 40.8 | 4.1 | 2.0 | 0.0 | 6.1 | 2.0 | 0.0 |
>3,700 | 305 (141–1,443) | 139 | 45 | 17.3 | 6.5 | 0.7 | 2.9 | 1.4 | 0.0 |
Radioiodine activity during year before conception (MBq) | |||||||||
0 | 0 | 290 | 46.6 | 12.8 | 8.0 | 1.0 | 3.4 | 1.7 | 1.0 |
<370 | 3.92 | 73 | 39.7 | 12.3 | 8.2 | 0.0 | 2.7 | 4.1 | 0.0 |
≥370 | 144.2 | 13 | 46.2 | 15.4 | 7.7 | 0.0 | 0.0 | 0.0 | 0.0 |