ROC Curve Analysis, Sensitivity, Specificity, PPV, and NPV
| Diastolic filling variable(s) | AUC | 95% Confidence interval for AUC | Optimal cutoff value(s) for detecting LVEDPs of ≥18 mm Hg | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|---|
| PFR | 0.83 | 0.72–0.95 | ≤2.57 EDV/s | 82 | 80 | 67 | 90 |
| TPFR | 0.75 | 0.62–0.89 | ≥161 ms | 88 | 63 | 54 | 92 |
| 1/3FR | 0.80 | 0.68–0.93 | ≤1.52 EDV/s | 82 | 74 | 61 | 90 |
| PFR + 1/3FR | ≤2.57 EDV/s + ≤1.52 EDV/s | 67 | 94 | 86 | 84 |