Patient Data
Age (y) at initial diagnosis of lesion | Location of lesion† | Reason for MRI‡ | Growth pattern on initial MRI | Mean L/B ratio for 18F-FET uptake in lesion on PET | Date (mo/y) of initial MRI leading to diagnosis of NIL | Clinical course | Radiologic course | Time after initial diagnosis until lesion resection (mo) | Histology of lesion after resection‖ | Time after initial diagnosis until death from disease (mo) | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Group* | Patient | Sex | Regression§ | Progression¶ | ||||||||||
A | 1 | 44 | M | R T | Collapse | Circumscribed | 1.0 | 05/2004 | Unchanged | 3 | ||||
2 | 54 | F | R F | Dizziness | Circumscribed | 1.1 | 02/2004 | Unchanged | 6 | |||||
3 | 35 | F | L T | Sudden deafness | Circumscribed | 1.3 | 07/2003 | Unchanged | 5 | |||||
4 | 25 | F | L O | Healthy volunteer | Circumscribed | 1.3 | 01/2003 | Unchanged | 4 | |||||
5 | 30 | F | R P | Dizziness | Circumscribed | 1.4 | 09/2004 | Unchanged | 10 | |||||
B | 6 | 39 | M | L F | Blurred vision | Circumscribed | 0.8 | 06/2003 | Unchanged | |||||
7 | 41 | M | R O | Antisocial behavior | Circumscribed | 1.0 | 04/2003 | Unchanged | ||||||
8 | 37 | F | L F | Migraine | Circumscribed | 1.0 | 11/2004 | Unchanged | ||||||
9 | 64 | M | L O | Blurred vision | Circumscribed | 1.0 | 03/2004 | Unchanged | ||||||
10 | 51 | F | R T | Headaches | Circumscribed | 1.0 | 01/2001 | Unchanged | ||||||
11 | 11 | F | L F | Headaches | Circumscribed | 1.0 | 01/2003 | Unchanged | ||||||
12 | 74 | F | R F | Headaches | Circumscribed | 1.0 | 06/2004 | Unchanged | ||||||
13 | 38 | F | R F | Healthy volunteer | Circumscribed | 1.0 | 02/2002 | Unchanged | ||||||
14 | 13 | F | R F | Antisocial behavior | Circumscribed | 1.0 | 08/2003 | Unchanged | ||||||
15 | 28 | F | R F | Dizziness | Circumscribed | 1.1 | 05/1999 | Unchanged | ||||||
C | 16 | 29 | F | R F | Collapse | Circumscribed | 0.7 | 07/2000 | Unchanged | 27 | 75 | A II | ||
17 | 42 | F | R F | Headaches | Circumscribed | 1.0 | 05/2001 | Unchanged | 21 | 69 | A II | |||
D | 18 | 36 | M | R P | Sudden deafness | Diffuse | 1.6 | 10/2003 | Deterioration | 40 | 41 | A III | ||
19 | 61 | F | R P | Dizziness | Diffuse | 1.7 | 06/2002 | Deterioration | 13 | 13 | GB IV | 17 | ||
20 | 49 | F | L F | Migraine | Diffuse | 2.3 | 10/2001 | Deterioration | 13 | 13 | GB IV | 22 | ||
21 | 38 | M | R F | Headaches | Diffuse | 2.4 | 08/2003 | Deterioration | 2 | 2 | GB IV | 42 |
↵* A: lesions that regressed; B: lesions that were stable, without growth; C: lesions with continuous and slow growth; D: lesions with sudden and rapid growth.
↵† R = right hemispheric; T = temporal; F = frontal; L = left hemispheric; O = occipital; P = parietal.
↵‡ Nonspecific symptom or reason leading to initial imaging.
↵§ Time interval in months until decrease in lesion size of at least 30%.
↵¶ Time interval in months until increase in lesion size of at least 30%.
↵‖ A II = astrocytoma of WHO grade II; A III = anaplastic astrocytoma of WHO grade III; GB IV = glioblastoma of WHO grade IV.