Comparison of Ki Estimates from Measured and Estimated Input Functions from Mouse Data (n = 17)
| Input function type | Statistics of Ki* | Myocardium | Brain | Muscle |
|---|---|---|---|---|
| Measured | Estimate (1/min) | 0.1381 ± 0.0655 | 0.0291 ± 0.0170 | 0.0112 ± 0.0082 |
| IDIF, no correction | Estimate (1/min) | 0.0039 ± 0.0041 | <10−5 | <10−5 |
| Error (%) | −94.8 ± 7.3 | −99.9 ± 0.00 | −99.7 ± 1.11 | |
| Corr. coefficient | −0.664 | −0.336 | 0.191 | |
| t test P value | <10−5 | <10−5 | 3.7 × 10−5 | |
| MCIF, 0-sample | Estimate (1/min) | 0.1321 ± 0.0696 | 0.0225 ± 0.0122 | 0.0092 ± 0.0063 |
| Error (%) | −3.0 ± 21.7 | −13.3 ± 31.5 | −7.8 ± 29.3 | |
| Corr. coefficient | 0.869 | 0.843 | 0.945 | |
| t test P value | 0.487 | 0.011 | 0.016 | |
| MCIF, 1-sample | Estimate (1/min) | 0.1414 ± 0.0785 | 0.0268 ± 0.0168 | 0.0106 ± 0.0076 |
| Error (%) | −1.7 ± 21.8 | −8.2 ± 17.5 | 1.6 ± 28.0 | |
| Corr. coefficient | 0.924 | 0.911 | 0.969 | |
| t test P value | 0.669 | 0.200 | 0.289 |
↵* Estimate (1/min) and error (%) are expressed as mean ± SD.
Corr. coefficient = correlation coefficient.