Comparison of Ki Estimates from Measured and Estimated Input Functions from Rat Data (n = 20)
| Input function type | Statistics of Ki* | Myocardium | Brain | Muscle |
|---|---|---|---|---|
| Measured | Estimate (1/min) | 0.0417 ± 0.0224 | 0.0156 ± 0.0061 | 0.0023 ± 0.0012 |
| IDIF, no correction | Estimate (1/min) | 0.0112 ± 0.0046 | 0.0027 ± 0.0046 | 0.0001 ± 0.0002 |
| Error (%) | −69.7 ± 9.9 | −83.5 ± 21.7 | −92.9 ± 14.7 | |
| Corr. coefficient | 0.886 | 0.486 | 0.183 | |
| t test P value | <10−5 | <10−5 | <10−5 | |
| MCIF, 0-sample | Estimate (1/min) | 0.0410 ± 0.0229 | 0.0145 ± 0.0066 | 0.0020 ± 0.0010 |
| Error (%) | −2.2 ± 20.8 | −5.7 ± 25.4 | −11.1 ± 33.8 | |
| Corr. coefficient | 0.928 | 0.808 | 0.708 | |
| t test P value | 0.719 | 0.269 | 0.087 | |
| MCIF, 1-sample | Estimate (1/min) | 0.0464 ± 0.0308 | 0.0164 ± 0.0075 | 0.0023 ± 0.0016 |
| Error (%) | 6.1 ± 20.1 | 4.2 ± 20.3 | −0.8 ± 21.9 | |
| Corr. coefficient | 0.948 | 0.861 | 0.917 | |
| t test P value | 0.091 | 0.329 | 0.883 |
↵* Estimate (1/min) and error (%) are expressed as mean ± SD.
Correlation coefficient (Corr. coefficient) and P values are calculated from the (Kimea, Kiest) pairs.