General Group Characteristics at Both Baseline and After Intervention (Either Sham Operation or MI)
| Parameter | Sham | MI |
|---|---|---|
| General characteristics | ||
| Weight (g) | 184 ± 7 | 182 ± 9 |
| Heart rate (bpm) | 323 ± 20 | 330 ± 15 |
| Cardiac function parameters | ||
| Baseline | ||
| LVEDD (mm) | 61.4 ± 0.8 | 62.5 ± 1.9 |
| LVEDSD (mm) | 30.4 ± 1.7 | 28.7 ± 5.0 |
| LV FS (%) | 50.4 ± 3.5 | 54.1 ± 5.9 |
| Postoperatively | ||
| LVEDD (mm) | 62.5 ± 1.9 | 72.0 ± 6.5 |
| LVESD (mm) | 32.4 ± 2.8 | 56.8 ± 4.5 |
| LV FS (%) | 47.8 ± 2.8 | 20.7 ± 3.4* |
↵* P = 0.003 compared with sham.
LVEDD = left ventricular end-diastolic diameter; LVESD = left ventricular end-systolic diameter; LV FS = left ventricular fractional shortening.
There was no difference in weight, heart rate, or baseline parameters of cardiac function. After MI, there was a decrease in cardiac function, as evidenced by a decrease in fractional shortening, whereas in sham animals cardiac function was preserved.