Overall Grade of Evidence: Quality of Primary Research plus Quality of Systematic Reviews
| Grade | Definition |
|---|---|
| High-quality evidence | High-quality systematic reviews with high-quality evidence and consistent findings |
| Moderate-quality evidence | High-quality or moderate-quality systematic reviews with moderate- quality evidence and consistent findings |
| Low-quality evidence | High-, moderate-, low-, or unclear- quality systematic reviews with low-quality or unclear evidence and consistent or inconsistent findings |
| Moderate-quality systematic reviews with moderate-quality evidence and inconsistent findings |