Characteristics of SPECT and PET Radiopharmaceuticals
| Modality | Tracer | Usual dose (MBq) | Photon energy (keV) | Time to imaging from injection | Physical half-life | Comments |
|---|---|---|---|---|---|---|
| SPECT | 201Tl | 111–166.5 | 80 | 1–15 min | 73 h | Potassium analog |
| Redistribution with time | ||||||
| 99mTc-Sestamibi | Mitochondrial uptake | |||||
| 296–1,480 | 140 | 15–45 min | 6 h | Cationic and lipophilic | ||
| 99mTc-Tetrofosmin | No significant redistribution | |||||
| PET | 82Rb | 1,110–2,220 | 511 | 80 s | 75 s | Potassium analog |
| Generator produced | ||||||
| 13N-Ammonia | 370–740 | 511 | 6 min | 10 min | ATP-dependent trapping in cytoplasm | |
| Requires on-site cyclotron |