Patient Data
| Patient no. | Age (y) | TNM stage | Tu size (cm) | SUV Tu | SUV LN | SUV Met | Staining pattern IHC αvβ3 |
|---|---|---|---|---|---|---|---|
| 1 | 73 | pT2 pN1a pMXR0 | 4.0 | 3.6 | Neg. | — | Tumor cells and vessels positive, moderate |
| 2 | 38 | ypT0 N0 M0 | NA* | NA* | NA* | NA* | |
| 3 | 64 | pT3 pN3a pMXR0 | 3.0 | 4.3 | Neg. | — | Tumor cells and vessels positive, intense |
| 4 | 63 | pT2m pN3a MXR0 | 4.5 | 2.5 | 2.2 | — | Tumor vessels positive, weak |
| 1.5 | 1.5 | ||||||
| 5 | 73 | pT2 pN0 MXR0 | 4.0 | 8.7 | — | — | Tumor cells and vessels positive, intense |
| 6 | 40 | NA† | — | — | — | — | |
| 7 | 73 | pT2 pN2a pMXR0 | 2.0 | 3.0 | Neg. | — | |
| 8 | 68 | pT2 pN0 MXR1 | 2.1 | 3.1 | — | — | |
| 9 | 70 | pT4b pN2a(4/5) cM1R1 | 6.0 | 3.6 | 3.5 | 3.8 | |
| 1.2 | |||||||
| 10 | 70 | cT4c N2c M1 | 4.0 | 4.1 | 4.1 | 3.1 | Tumor vessels positive, weak |
| 11 | 68 | pT1c pN1(sn1/1) pMX | 1.6 | 2.8 | Neg. | — | |
| 12 | 44 | pT4b N3a MXR0 | 4.5 | 3.2 | Neg. | — | |
| 13 | 54 | pT3c N0 M1 | 2.0 | 3.8 | — | 2.8 | |
| 3.0 | |||||||
| 14 | 66 | pT3c N2c M1 | — | — | — | 2.2 | |
| 3.0 | |||||||
| 3.3 | |||||||
| 15 | 68 | pT4c N1 M0 | 7.0 | 2.3 | — | — | |
| 16 | 65 | pT2m N1 M1biv | NA | NA | NA | 2.6 |
↵* No viable tumor cells found after neoadjuvant chemotherapy.
↵† Tumor suspected according to MR mammography (BIRADS 4), no tumor histopathologically.
Tu size = maximum tumor diameter (cm); SUV Tu, SUV LN, and SUV Met = tracer uptake as standardized uptake value (SUV) in tumors, lymph nodes, and distant metastases; IHC αvβ3 = immunohistochemistry with αvβ3-specific antibody LM609; Neg. = negative; NA = not applicable.