Goals of Imaging Modalities by Clinical State in Prostate Cancer
| Clinical state | Imaging objective |
|---|---|
| Initial prostate evaluation (no cancer diagnosis) | Distinguish cancer from benign tissue |
| Clinically localized disease | Identify extent of both localized and metastatic disease |
| Prognosticate | |
| Identify treatment effects | |
| Rising PSA (castration-sensitive and -resistant) | Identify extent of both localized and metastatic disease to guide therapy |
| Clinical metastases (castration-sensitive and -resistant) | Determine extent of metastatic disease |
| Assess treatment response | |
| Identify patients with a particular biologic profile | |
| Prognosticate | |
| Determine pharmacodynamics of targeted therapy |