Indications for 18F-Fluoride Skeletal PET
| Type of disease | Type of assessment | Specific goal |
|---|---|---|
| Oncologic | Metastatic disease in skeleton (e.g. prostate, lung, breast, neuroblastoma) | Perform initial evaluation (staging) |
| Assess response of skeletal metastases to therapy | ||
| Detect skeletal metastases during follow-up | ||
| Bone pain in patients with known cancer | ||
| Primary bone tumors | Identify sites of disease (initial staging) | |
| Assess response to therapy | ||
| Differentiate postoperative changes from residual/recurrent disease | ||
| Detect recurrent/metastatic disease during follow-up | ||
| Benign bone | Pediatric/young adult back pain | Assess vertebral spondylolysis |
| Assess other stress injuries | ||
| Bone viability | Assess femoral head avascular necrosis | |
| Assess bone graft viability (long bones, mandible) | ||
| Paget's disease | Assess extent of disease | |
| Monitor response to therapy |