Tumor Blood Flow and Uptake of 18F-FDG and 18F-EF5
| Blood flow (mL/100 g/min) | Uptake of 18F-FDG | Uptake of 18F-EF5 3 h after injection | ||||
|---|---|---|---|---|---|---|
| Patient no. | Max SUV | Mean SUV | Mean T/M | Max T/M | PHA | |
| 1 | 54.84 | 4.80 | 3.74 | 1.49 | 1.75 | 34.7 |
| 2 LN* | 78.55 | 4.13 | 2.53 | 1.20 | 1.39 | 0 |
| 3 | 70.72 | 12.67 | 8.58 | 1.05 | 1.15 | 0 |
| 4 | 28.09 | 5.35 | 2.33 | 1.27 | 1.52 | 66.7 |
| 5 | 39.64 | 22.06 | 14.08 | 1.20 | 1.20 | 0 |
| 6 | 36.69 | 5.71 | 2.70 | 1.46 | 1.64 | 29.9 |
| 7 | 52.33 | 10.84 | 7.69 | 1.21 | 1.35 | 0 |
| LN | 35.26 | 8.39 | 6.33 | 1.84 | 2.29 | 64.3 |
| 8 | 25.92 | 6.35 | 4.74 | 1.38 | 1.74 | 7.6 |
| LN | 43.53 | 5.17 | 3.67 | 1.37 | 1.62 | 8 |
| 9 | 23.26 | 7.98 | 6.49 | 3.34 | 4.07 | 86.8 |
| LN | 30.96 | 5.45 | 3.93 | 1.90 | 2.63 | 44.9 |
| 10 | 40.24 | 10.56 | 7.16 | 1.51 | 1.90 | 20.8 |
| LN | 29.66 | 8.48 | 4.68 | 1.37 | 1.74 | 34.5 |
| 11 | 31.87 | 4.56 | 3.56 | 1.33 | 1.65 | 11.1 |
| 12 | 30.96 | 7.46 | 4.90 | 1.37 | 1.91 | 40 |
| 13 | 49.56 | 9.12 | 7.68 | 1.76 | 2.02 | 50.4 |
| 14 | † | 8.66 | 6.10 | 1.70 | 2.26 | 49,3 |
↵* Patient 2 had primary tumor excised before scanning.
↵†Input curve was lost because of technical difficulties.
SUV = standardized uptake value; PHA = percentage hypoxic area (SUV) of 18F-FDG, and hypoxic fraction (PHA) as percentage of voxels above T/M = 1.5 3 h after injection of 18F-EF5.
LN designates lymph node metastasis of preceding patient. Metabolism is expressed as SUV.