Management | Before PET (n) | After PET (n) | Changed* (n) | Change in diagnosis specified† |
---|---|---|---|---|
Expert 1 | ||||
Local therapy‡ | 17 | 14 | 10 | |
Surgery (1) | 6 | 5 | 2 | 1→6 (2×) |
Radiotherapy (2) | 7 | 6 | 4 | 2→6 (4×) |
Hyperthermia (3) | 5 | 3 | 4 | 3→2, 3→5, 3→6 (2×) |
Systemic therapy | 11 | 9 | 6 | |
Chemotherapy (4) | 6 | 3 | 3 | 4→2, 4→5, 4→6 |
Palliative treatment (5) | 5 | 6 | 3 | 5→1, 5→3, 5→4 |
Expectative (6) | 12 | 17 | 4 | 6→1, 6→2, 6→5 (2×) |
Curative§ | 26 | 26 | 4 | Curative→palliative (4×) |
Palliative | 14 | 14 | 2 | Palliative→curative (2×) |
Expert 2 | ||||
Local therapy‡ | 13 | 13 | 7 | |
Surgery (1) | 0 | 2 | 0 | — |
Radiotherapy (2) | 7 | 8 | 4 | 2→4, 2→6 (3×) |
Hyperthermia (3) | 5 | 3 | 3 | 3→4, 3→6 (2×) |
Systemic therapy | 6 | 6 | 6 | |
Chemotherapy (4) | 6 | 6 | 3 | 4→2 (3×) |
Palliative treatment (5) | 0 | 0 | 0 | — |
Expectative (6) | 22 | 21 | 6 | 6→1 (2×), 6→2 (2×), 6→3, 6→4 |
Curative§ | 22 | 24 | 2 | Curative→palliative (2×) |
Palliative | 18 | 16 | 6 | Palliative→curative (4×) |
↵* Number of cases in which pre-PET management plan was changed after 18F-FDG PET.
↵† Change in management specified: 1, surgery; 2, radiotherapy; 3, hyperthermia; 4, chemotherapy; 5, palliative treatment; and 6, expectative.
↵‡ Local therapy for localized recurrence that could be combined with other treatment modalities. Surgery could be combined with radiotherapy, chemoradiation, hyperthermia, or chemotherapy. Radiotherapy could be combined with hyperthermia or chemotherapy. Hyperthermia could be combined with chemotherapy.
↵§ Management plans of patients without suspicion of recurrence were classified under curative intent.