TABLE 4

Summary by Testing Indication for All Cancer Types in NOPR

Testing indication	No. of scans	% of cases with change in management^*	95% CI	Imaging-adjusted impact (%)^†	95% CI
Initial staging	14,365	39.8	39.0–40.6	13.4	12.8–13.9
Restaging	14,584	35.9	35.1–36.7	12.6	12.0–13.1
Detection of suspected recurrence	11,914	38.5	37.6–39.3	18.8^‡	18.1–19.5
Total	40,863	38.0	37.6–38.5	14.7	14.3–15.0

↵* Defined as change from treatment to nontreatment or as change from nontreatment to treatment.
↵† No benefit from PET was assumed for cases with imaging plan before PET.
↵‡ Odds ratio relative to that for other indications was 1.56 (CI = 1.47–1.65).