TABLE 6

Sensitivity of ¹⁸F-FDG and ¹¹C-Acetate PET/CT in 28 Patients with Metastatic HCC: Lesion-Based Analysis of 35 Index Lesions

		¹⁸F-FDG		¹¹C-acetate
Characteristic	No. of lesions (n = 35)	Lesions positive (n)	P	Lesions positive (n)	P	P^* between 2 PET/CT types
Tumor size (cm)
≥1, <2	20	16 (80)	NS	13 (65)	NS	NS
≥2	15	14 (93)		14 (93)		NS
			NS^†		0.052^†
Metastasis location
Lung	20	16 (80)	NS	14 (70)	NS	NS
Bone	6	6 (100)		6 (100)
Adrenal gland	4	3 (75)		3 (75)
Abdominal peritoneum	3	3 (100)		2 (66.7)
Brain	1	1 (100)		1 (100)
Left atrium of heart	1	1 (100)		1 (100)
Tumor differentiation^‡
Grade I and II	22	20 (91)	NS	20 (91)	0.032	NS
Grade III and IV	13	10 (77)		7 (54)		NS
			NS^†		0.013^†

↵* Comparison of positives between ¹⁸F-FDG and ¹¹C-acetate PET/CT according to tumor characteristics using McNemar χ² test.
↵† Score test for trend.
↵‡ Edmonson–Steiner grade.
NS = not significant.
Data in parentheses are sensitivity (%).