TABLE 3

Lesion Uptake of 18F-FDG and 11C-Acetate on PET/CT: Patient-Based Analysis of 90 Patients with Primary HCC

18F-FDG11C-acetate
CharacteristicNo. of patients (n = 90)Patients with all lesions positive (n)PPatients with all lesions positive (n)PP* between 2 PET/CT types
Tumor size (cm)
 ≥1, <270 (0)<0.0012 (29)0.030NS
 ≥2, <54218 (43)29 (69)0.003
 ≥54132 (78)32 (78)NS
<0.0010.023
Tumor number
 14626 (57)0.00136 (78)0.0010.006
 2–3142 (14)4 (29)NS
 ≥43022 (73)23 (77)NS
NSNS
Tumor type
 Well defined7842 (54)NS55 (71)NS0.002
 Ill defined128 (67)8 (67)NS
Portal vein invasion
 No6329 (46)0.00543 (68)NS0.001
 Yes2721 (78)20 (70)NS
  • * Comparison of positives between 18F-FDG and 11C-acetate PET/CT according to tumor characteristics using McNemar χ2 test.

  • Score test for trend.

  • NS = not significant.

  • Data in parentheses are percentages.