TABLE 1

Biodistribution of 90Y-AABD (n = 3)

1 h after injection24 h after injection
DAbR1-expressing U-87 groupWild-type U-87 groupDAbR1-expressing U-87 groupWild-type U-87 group
Region%ID/gSD%ID/gSD%ID/gSD%ID/gSD
Tumor6.231.320.160.024.890.620.050.03
RBC0.030.010.020.010.000.000.010.01
Plasma0.160.010.050.010.010.000.020.01
Heart0.080.010.20.030.020.010.020.01
Liver2.970.913.381.510.790.331.080.54
Brain0.100.120.020.000.010.000.060.08
Stomach0.320.010.660.130.040.020.310.42
Small intestine1.611.260.870.210.260.350.020.00
Colon1.320.372.481.790.030.010.070.01
Spleen0.690.510.960.611.300.470.450.19
Kidney0.830.011.671.090.140.050.140.11
Skeletal muscle0.500.350.070.010.010.000.020.02
Skin0.380.380.310.240.020.000.070.05
Femur0.570.560.180.150.190.130.180.16
  • RBC = red blood cell.