Scenario | ||||
---|---|---|---|---|
Parameter | A | B | C | D |
FN cases (n) | 5* + 4† | 5* | 2* + 4† | 1* |
TP cases (n) | 19‡ | 23‡ | 19‡ + 3§ | 23‡ + 4§ |
FN rate | 9/(9 + 19) | 5/(5 + 23) | 6/(6 + 22) | 1/(1 + 27) |
FN rate (%) | 32.14 | 17.86 | 21.43 | 3.57 |
↵* Local recurrences observed.
↵† Additional false-negative cases, which would have been potentially observed if only hottest node had been harvested.
↵‡ Patients with SLN classified as metastatic by PATH.
↵§ Patients PATH negative and PCR positive with nodal recurrence during long-term follow-up.
FN = false-negative; TP = true-positive.
FN rate = FN/(FN + TP).
FN rate (%) = (FN/[FN + TP]) × 100.