Patient Characteristics
| Patient no. | Age (y) | Leukemia subtype (World Health Organization) | Verification of disease activity (% blasts) | Mean 18F-FLT uptake | |||
|---|---|---|---|---|---|---|---|
| Sex | Remission status | BM | Spleen | ||||
| 1 | 36 | F | AML with abnormal bone marrow eosinophils inv(16) | Initial diagnosis | 51%−75% (BM) | 13.6 | 5.4 |
| 2 | 51 | F | AML with multilineage dysplasia | Refractory (BM) | 100% (BM) | 15.6 | 7.5 |
| 3 | 48 | F | AML, acute monoblastic leukemia | Relapse | 40% (BM) | 9.8 | 16.8 |
| 4 | 42 | M | AML with t(8;21) | Relapse (BM + EM) | 99% (PB) | 11.0 | 8.6 |
| 5 | 43 | M | AML minimally differentiated | Relapse (BM) | 100% (BM) | 9.5 | 6.4 |
| 6 | 23 | F | AML, acute monoblastic leukemia | Relapse (BM) | 50% (BM) | 12.5 | 6.7 |
| 7 | 65 | M | AML, acute monoblastic leukemia | Relapse (EM) | Blasts in ascites, liquor, lymph nodes, testicles | 8.9* | 1.9 |
| 8 | 54 | F | AML | Relapse | 80% (BM), 94% (PB) | 12.4 | 16.8 |
| 9 | 70 | M | AML with multilinear dysplasia | Refractory | 20%−25% (BM), 5%−10% (PB) | 15.4 | 5.8 |
| 10 | 36 | F | AML, acute myelomonocytic leukemia | Second CR | <5% (BM) | 8.2 | 2.3 |
| 11 | 38 | M | AML, minimally differentiated | First CR, graft rejection | <5% (BM) | 0.7 | 0.6 |
↵* Extramedullary lesion.
BM = bone marrow; EM = extramedullary lesion; PB = peripheral blood; CR = complete remission.