TABLE 1

Rate Constants for Each Brain Region Determined by Kinetic Approach Using 3CM with Arterial Input Function

	Rate constant
Region	K₁ (mL/mL/min)	k₂ (min⁻¹)	k₃ (min⁻¹)	k₄ (min⁻¹)	Total distribution volume
Putamen	0.111 ± 0.019	0.036 ± 0.016	0.081 ± 0.040	0.014 ± 0.003	21.3 ± 3.4
Caudate	0.088 ± 0.018	0.023 ± 0.018	0.061 ± 0.067	0.011 ± 0.005	21.5 ± 1.7
Parahippocampus	0.140 ± 0.023	0.033 ± 0.007	0.027 ± 0.020	0.015 ± 0.006	11.3 ± 1.4
Occipital lobe	0.127 ± 0.017	0.065 ± 0.038	0.089 ± 0.057	0.021 ± 0.007	10.0 ± 1.1
Temporal lobe	0.106 ± 0.050	0.050 ± 0.025	0.067 ± 0.038	0.020 ± 0.003	9.5 ± 0.9
Frontal lobe	0.108 ± 0.011	0.041 ± 0.011	0.052 ± 0.023	0.021 ± 0.002	9.1 ± 0.9
Anterior cingulate cortex	0.115 ± 0.014	0.064 ± 0.018	0.072 ± 0.027	0.019 ± 0.005	8.8 ± 0.9
Thalamus	0.112 ± 0.019	0.043 ± 0.018	0.038 ± 0.026	0.019 ± 0.003	7.6 ± 0.9
Cerebellum
3CM	0.115 ± 0.017	0.051 ± 0.015	0.017 ± 0.008	0.013 ± 0.003	5.2 ± 0.4
2CM	0.089 ± 0.014	0.019 ± 0.002			4.6 ± 0.3

Values are mean ± SD. For cerebellum, both 2CM and 3CM were applied.