TABLE 2
Organ- and Tissue-Absorbed Doses Normalized to Administered Activity for 18F-AH111585
| Administered activity (μGy/MBq) | ||
|---|---|---|
| Organ/tissue | Mean | SD |
| Adrenals | 15 | 1 |
| Brain | 6 | 1 |
| Breasts | 7 | 1 |
| Gallbladder wall | 21 | 4 |
| Gastrointestinal tract | ||
| Lower large intestine wall | 23 | 7 |
| Small intestine wall | 44 | 22 |
| Stomach wall | 12 | 1 |
| Upper large intestine wall | 49 | 26 |
| Cardiac wall | 59 | 10 |
| Kidneys | 102 | 19 |
| Liver | 35 | 6 |
| Lungs | 30 | 3 |
| Muscle | 9 | 1 |
| Osteogenic cells | 12 | 1 |
| Ovaries | 17 | 3 |
| Pancreas | 15 | 1 |
| Red marrow | 10 | 0.5 |
| Skin | 6 | 1 |
| Spleen | 57 | 15 |
| Testes | 9 | 1 |
| Thymus | 10 | 1 |
| Thyroid | 17 | 21 |
| Urinary bladder wall | 124 | 29 |
| Uterus | 19 | 3 |
Mean effective dose per unit administered activity = 26 (±4)·
.