Summary of Data on Animals with Cortical Infarctions
| d-cis-FPro uptake | 3H-DG | 3H-PK11195 | 3H-MET | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Rat no. | Time after PT (d) | Cortical area | Thalamic nucleus, striatum | PT/brain | TN/brain | PT/brain | TN/brain | PT/brain | TN/brain | PT/brain | TN/brain |
| 1 | 7 | Mot, Sens | CPu, Po, VPM, VPL | 12.6 | 4.0 | ||||||
| 2 | 5 | Mot, Sens | CPu, Po, VL | 11.7 | 6.3 | 4.2 | 1.4 | ||||
| 3 | 8 | Vis | DLG, LP | 16.6 | 8.0 | 2.4 | 1.0 | ||||
| 4 | 7 | Sens, Vis | Po, VPM, DLG | 12.4 | 6.0 | 5.5 | 1.0 | ||||
| 5 | 7 | Vis | DLG, LP | 17.6 | 3.4 | 2.2 | 1.1 | ||||
| 6 | 7 | Mot, Sens | CPu, Po, VPM, VPL, VL | 9.4 | 4,0 | 3.0 | 1.2 | ||||
| 7 | 7 | Mot | CPu, VL | 16.8 | 4.8 | 3.0 | 1.0 | ||||
| 8 | 7 | Sens | Po, VPM, VPL | 10.7 | 9.0 | 2.7 | 0.9 | ||||
| 9 | 7 | Sens | Po, VPM, VPL | 6.6 | 5.6 | 2.3 | 0.8 | ||||
| 10 | 14 | Sens | Po, VPM, VPL | 31.6 | 11.8 | 5.7 | 1.4 | ||||
| 11 | 28 | Sens | Po, VPM | 4.1 | 9.6 | ||||||
| 12 | 28 | Sens | Po, VPM | 24.8 | 13.4 | ||||||
| 13 | 28 | Sens | Po, VPM | 7.0 | 9.3 | 8.0 | 1.0 | ||||
| 14 | 5 | Mot, Sens | CPu, Po, VPM | 11.8 | 3.5 | 2.7 | 1.1 | ||||
| 15 | 3 | Mot, Sens | CPu, Po, VPM | 13.4 | 3.4 | 1.0 | 0.8 | ||||
| 16 | 3 | Mot, Sens | CPu, Po, VPM | 20.8 | 2.4 | 0.6 | 0.9 | ||||
| 17 | 2 | Sens | — | 3.3 | — | 0.9 | — | ||||
| 18 | 2 | Sens | — | 3.8 | — | 0.7 | — | ||||
| 19 | 1 | Sens | — | 3.4 | — | 1.0 | — | ||||
| 20 | 1 | Sens | — | 3.8 | — | 0.6 | — | ||||
| Mean | 12.1 | 6.7 | 2.5 | 1.0 | 6.8 | 1.2 | 1.4 | 1.0 | |||
| SD | 8.1 | 3.5 | 1.5 | 0.2 | 1.7 | 0.3 | 1.1 | 0.2 | |||
PT = cortical infarction induced by photothrombosis; ; 3H-DG = 3H-deoxyglucose; 3H-Pk11195 = ligand for peripheral benzodiazepine receptors; 3H-MET = 3H-methyl-l-methionine; PT/brain = ratio of maximal tracer uptake PT divided by mean uptake in normal brain tissue; TN/brain = ratio of maximal tracer uptake in thalamic nucleus divided by mean uptake in normal brain; Mot = motor cortex; Sens = somatosensory cortex; CPu = caudate putamen; Po = posterior thalamic nuclear group; VPM = ventral posteromedial thalamic nucleus; VPL = ventroposterolateral thalamic nucleus; VL = ventrolateral thalamic nucleus; Vis = visual cortex; DLG = dorsal lateral geniculate nucleus; LP = lateral posterior thalamic nucleus.