TABLE 2

Test–Retest Characteristics of BP, Delivery in ROI Relative to Cerebellum (R₁), and Tracer Efflux Constant from Tissue to Plasma (k₂) Computed with SRTM with Actual ¹⁸F-MPPF Data of 10 Subjects

Actual SRTM BP Region	Test (mean ± SD)	Retest (mean ± SD)	Change in mean (%)	Typical error as CV (%)	ICC	Paired t test P
Hippocampus	1.43 ± 0.17	1.47 ± 0.16	2.48	7.30	0.57	0.426
Amygdala	1.16 ± 0.15	1.21 ± 0.16	4.04	8.68	0.57	0.270
Enthorinal cortex	1.25 ± 0.19	1.30 ± 0.16	4.80	7.43	0.73	0.188
Parhippocampal gyrus	0.90 ± 0.11	0.91 ± 0.10	1.67	4.67	0.84	0.474
Anterior cingulum	0.75 ± 0.09	0.74 ± 0.09	−1.15	9.08	0.50	0.771
Posterior cingulum	0.65 ± 0.07	0.65 ± 0.07	−0.47	6.12	0.67	0.876
Insula	0.96 ± 0.10	0.97 ± 0.11	−0.68	6.86	0.67	0.818
Temporal pole	0.91 ± 0.14	0.91 ± 0.12	−0.46	7.10	0.77	0.994
Temporal cortex	0.90 ± 0.11	0.90 ± 0.11	−0.02	5.32	0.81	0.986
Raphe	0.28 ± 0.08	0.28 ± 0.09	−0.50	14.97	0.78	0.944
Mean limbic area	0.92 ± 0.12	0.93 ± 0.12	0.97	7.75	0.69
Temporal neocortex	0.85 ± 0.10	0.84 ± 0.11	1.54	5.43	0.80	0.565
Lateral occipitotemporal gyrus	0.80 ± 0.13	0.77 ± 0.09	3.90	6.47	0.79	0.155
Frontal gyrus	0.61 ± 0.11	0.60 ± 0.11	1.85	7.36	0.83	0.564
Prefrontal cortex	0.53 ± 0.09	0.52 ± 0.11	1.68	7.14	0.84	0.703
Inferior parietal cortex	0.61 ± 0.13	0.59 ± 0.11	2.65	5.47	0.93	0.179
Superior parietal cortex	0.57 ± 0.10	0.55 ± 0.08	2.09	7.80	0.78	0.451
Occipital cortex	0.61 ± 0.12	0.60 ± 0.11	1.94	6.31	0.88	0.485
Occipital pole	0.40 ± 0.15	0.39 ± 0.16	1.56	14.30	0.87	0.900
Occipital gyrus	0.55 ± 0.11	0.53 ± 0.11	2.20	9.11	0.82	0.548
Mean other area	0.61 ± 0.12	0.60 ± 0.11	2.16	7.71	0.84
Actual SRTM R₁ Region	Test (mean ± SD)	Retest (mean ± SD)	Change in mean (%)	Typical error as CV (%)	ICC	Paired t test P
Hippocampus	0.79 ± 0.05	0.83 ± 0.09	5.21	7.86	0.13	0.175
Amygdala	0.73 ± 0.04	0.75 ± 0.06	3.00	6.36	0.23	0.309
Enthorinal cortex	0.76 ± 0.05	0.80 ± 0.06	4.18	4.96	0.35	0.090
Parhippocampal gyrus	0.82 ± 0.06	0.86 ± 0.09	4.87	5.96	0.54	0.097
Anterior cingulum	0.92 ± 0.07	0.96 ± 0.07	4.35	6.88	0.24	0.204
Posterior cingulum	0.94 ± 0.06	0.96 ± 0.07	2.83	4.87	0.53	0.228
Insula	0.97 ± 0.04	1.00 ± 0.09	−2.59	5.31	0.36	0.274
Temporal pole	0.73 ± 0.07	0.77 ± 0.07	−5.03	5.52	0.67	0.063
Temporal cortex	0.80 ± 0.07	0.83 ± 0.07	−3.74	5.42	0.59	0.161
Raphe	0.31 ± 0.01	0.32 ± 0.02	3.19	4.60	0.03	0.153
Mean limbic area	0.78 ± 0.05	0.81 ± 0.07	1.63	5.77	0.37
Temporal neocortex	0.91 ± 0.06	0.93 ± 0.07	−2.07	5.03	0.48	0.377
Lateral occipitotemporal gyrus	0.91 ± 0.06	0.95 ± 0.08	−3.63	5.80	0.45	0.176
Frontal gyrus	0.91 ± 0.05	0.93 ± 0.05	−2.65	5.73	0.05	0.324
Prefrontal cortex	0.91 ± 0.05	0.93 ± 0.05	−2.75	6.19	−0.17	0.327
Inferior parietal cortex	0.91 ± 0.04	0.94 ± 0.07	−2.83	6.34	−0.01	0.321
Superior parietal cortex	0.95 ± 0.04	0.97 ± 0.06	−2.54	5.56	−0.02	0.307
Occipital cortex	0.86 ± 0.08	0.90 ± 0.07	−4.66	6.35	0.46	0.126
Occipital pole	0.79 ± 0.08	0.83 ± 0.09	−4.74	7.24	0.51	0.163
Occipital gyrus	1.02 ± 0.07	1.08 ± 0.10	−5.00	5.55	0.52	0.064
Mean other area	0.91 ± 0.06	0.94 ± 0.07	−3.43	5.98	0.25
Actual SRTM k₂ Region	Test (mean ± SD)	Retest (mean ± SD)	Change in mean (%)	Typical error as CV (%)	ICC	Paired t test P
Hippocampus	0.25 ± 0.04	0.24 ± 0.02	−2.83	9.66	0.45	0.417
Amygdala	0.25 ± 0.04	0.25 ± 0.02	−1.26	11.58	0.21	0.648
Enthorinal cortex	0.23 ± 0.03	0.22 ± 0.02	−4.42	9.64	0.37	0.250
Parhippocampal gyrus	0.27 ± 0.04	0.27 ± 0.04	1.69	7.25	0.77	0.707
Anterior cingulum	0.32 ± 0.04	0.31 ± 0.03	−2.88	13.36	−0.03	0.574
Posterior cingulum	0.30 ± 0.03	0.30 ± 0.04	0.24	8.69	0.47	0.929
Insula	0.29 ± 0.04	0.28 ± 0.03	1.22	9.48	0.46	0.713
Temporal pole	0.24 ± 0.03	0.24 ± 0.02	0.14	7.67	0.55	0.923
Temporal cortex	0.27 ± 0.03	0.26 ± 0.03	1.21	10.00	0.35	0.763
Raphe	0.11 ± 0.01	0.11 ± 0.01	1.90	7.66	0.41	0.573
Mean limbic area	0.25 ± 0.03	0.25 ± 0.03	−0.50	9.50	0.40
Temporal neocortex	0.27 ± 0.04	0.27 ± 0.03	0.64	10.09	0.40	0.832
Lateral occipitotemporal gyrus	0.31 ± 0.04	0.32 ± 0.03	−3.81	9.05	0.36	0.387
Frontal gyrus	0.29 ± 0.03	0.29 ± 0.03	−0.02	8.77	0.23	0.977
Prefrontal cortex	0.29 ± 0.03	0.29 ± 0.03	−0.35	9.65	0.33	0.939
Inferior parietal cortex	0.30 ± 0.04	0.29 ± 0.04	2.25	12.18	0.20	0.699
Superior parietal cortex	0.32 ± 0.04	0.32 ± 0.04	0.01	10.43	0.35	0.991
Occipital cortex	0.29 ± 0.04	0.29 ± 0.03	−0.09	11.66	0.15	0.988
Occipital pole	0.27 ± 0.04	0.27 ± 0.05	1.14	13.34	0.32	0.907
Occipital gyrus	0.34 ± 0.04	0.35 ± 0.05	−4.39	9.58	0.42	0.282
Mean other area	0.30 ± 0.04	0.30 ± 0.04	−0.51	10.53	0.31