Blood and Whole-Body Clearances for Each of the 4 SHALs Given to Mice Intravenously in 1- or 20-μg Doses
| Blood half-time (h) | ||
|---|---|---|
| SHAL code | 1 μg (P value) | 20 μg (P value) |
| LeacPLDDo | 5.7 (0.3) | 3.9 (<0.01) |
| ItPLDDo | 5.5 (0.01) | 4.3 (<0.01) |
| DvLPTPLDo | 7.1 (0.16) | 4.0 (0.06) |
| DvLPBaPLDo | 4.6 (0.02) | 4.7 (0.05) |
| Whole-body half-time (h) | ||
| 1 μg (P value) | 20 μg (P value) | |
| LeacPLDDo | 7.7 (<0.01) | 7.5 (0.01) |
| ItPLDDo | 18.8 (<0.01) | 20.1 (<0.01) |
| DvLPTPLDo | 6.3 (0.01) | 7.1 (0.05) |
| DvLPBaPLDo | 5.5 (0.02) | 6.1 (0.05) |
P value reflects goodness of monoexponential fit.