TABLE 2

Data for 4 Bidentate DOTA-SHALs Evaluated in Mice

ParameterMedianRange
DOTAs available (%)5050–60
Radiochemical yield (%)9075–95
Product yield (%)7550–90
Product purity (%)9080–97
Specific activity (MBq/nM)6.63.8–10.6
Specific activity (MBq/μg)3.92.1–5.3
  • Data for 4 other bidentate DOTA-SHALs that were synthesized were similar.