Location of Microglial Cells and Morphology
| Endotoxin group | ||||
|---|---|---|---|---|
| Site | Control group | 20 μg/kg | 30 μg/kg | 40 μg/kg |
| Frontal cortex | − | − | − | − |
| Corpus callosum: along inferior border of lateral ventricle | ± | + | ++ | +++ |
| Rm | Bu | Bu, Ro, Am | Ro, Am | |
| Internal capsule | + | +++ | +++ | ++ |
| Rm | Bu | Bu, Ro, Am | Ro, Am | |
| External capsule | − | − | − | − |
| Around angle of lateral ventricle (at level of thalamus) | ++ | ++ | +++ | +++ |
| Rm | Bu | Bu, Ro, Am | Bu, Ro, Am | |
| Thalamus | − | − | − | − |
| Parietal cortex | − | − | − | − |
| Hippocampus | ||||
| Between 2 fields of hippocampus | + | +++ | +++ | +++ |
| Rm | Bu | Ro, Am | Ro, Am | |
| Dentate gyrus | + | + | + | +++ |
| Rm | Bu | Ro, Am | Ro, Am | |
| Fimbria hippocampus | + | ++ | ++ | +++ |
| Rm | Rm | Bu, Ro, Am | Ro, Am | |
− = no microglial cells; ± = rare microglial cells; + = few microglial cells; ++ = some microglial cells; +++ = many microglial cells; Rm = ramified cells; Bu = bushy cells; Ro = round cells; Am = amoeboid cells.